How many people have tried retatrutide and what was your experience?

I take my 3rd dose tomorrow. I did 2mg to start and 2.5 last weekend. I’ve noticed some appetite suppression and for sure feeling full quicker and for a longer period of time. No ill side effects yet. But as a lifetime of eating what I want, when I want and the issues that arrive with it, Reta hasn’t started melting anything off yet. I’ll stay the course. I might bump up again tomorrow. Or start splitting doses. Curious to see how this stuff works out.
Took ozempic for almost 2 years to lower A1C and lose weight. A1C went down drastically but never got the weight loss
 
I take my 3rd dose tomorrow. I did 2mg to start and 2.5 last weekend. I’ve noticed some appetite suppression and for sure feeling full quicker and for a longer period of time. No ill side effects yet. But as a lifetime of eating what I want, when I want and the issues that arrive with it, Reta hasn’t started melting anything off yet. I’ll stay the course. I might bump up again tomorrow. Or start splitting doses. Curious to see how this stuff works out.
Took ozempic for almost 2 years to lower A1C and lose weight. A1C went down drastically but never got the weight loss
Did ozempic lower your A1C because you ate less carbs over all or did it work in another way?
 
Retas been blowing up on facebook. Curious who has tried it and if they liked it or not. Id like to try it out.
I think its blowing up for good reason. Im so thankful for it. Been on for a few months with great results but I had to go through finding the right supplier bc the first few I ordeed from did not work at all. I eventually found a really good one luxpeptides.ca with clean good product and fast shipping.
 
For those who have used retatrutide intermittently, how long were you off before restarting? Did appetite suppression return at your initial starting dose?

I lost the appetite suppression at around 2-3 mg per week and didn't want to increase the dose or stay on indefinitely, so am interested if anyone took a break from it and whether that helped reset the way they respond to it.
 
I have never felt the need to go over two I bounce around 1.5 to 2mg a week awesome tool of used correctly start low titrate up personally with how strong it is I don't see why people go over 2-3mg
 
For those who have used retatrutide intermittently, how long were you off before restarting? Did appetite suppression return at your initial starting dose?

I lost the appetite suppression at around 2-3 mg per week and didn't want to increase the dose or stay on indefinitely, so am interested if anyone took a break from it and whether that helped reset the way they respond to it.
I just got off of it this week, so I’ll get back to you with my observations at a later date on this. I’ve been on Reta for just over a year.
 
I got a lot more out of tirzepatide than reta. More appetite supression and went to basically zero visceral fat on dexa scan. Used both at typical starting doses, never went up.

Reta for me seemed like I would need to titrate up reta to get the same effect - not worth the trouble.
 
I got a lot more out of tirzepatide than reta. More appetite supression and went to basically zero visceral fat on dexa scan. Used both at typical starting doses, never went up.

Reta for me seemed like I would need to titrate up reta to get the same effect - not worth the trouble.
Good that Tirz worked for you Reta isn’t known for the hunger suppression but it is more effective outside of that part. I’ve dropped 47.7lbs with Reta and destroyed the visceral fat, liver fat and more. Fixed cholesterol, blood pressure, heart rate, blood sugar and more. Still 232lbs now I melted the fat off with Reta. Number 1 compound I’ve ever tried by a mile.
 
Works great. I easily lost abiut 20lbs in 12 weeks. The only thing I did not like was the slower digesting. Pre training meals took forever to digest.
 
Works great. I easily lost abiut 20lbs in 12 weeks. The only thing I did not like was the slower digesting. Pre training meals took forever to digest.
I haven’t experienced this too much fortunately.
 
Reta seems to impact people differently. If you suffer from anxiety but have it under control, per the comments above - it appears to exacerbate the issue.

That is a guess as it is still under controlled studies and has some negative health side effects, but from a fat burning peptide it is impressive.
If you have any pre-existing mental diseases (no different than diabetes and people should be proud to admit these diseases with a stigma, are an issue.) I would start out at .25 mg and titrate up every 2 weeks by .25 of a mg.

I can still eat, but when I increase it by .25 mg a week I notice it is hard to get my portions/meals down which I do so by eating more often in smaller amounts. I am only on a mild deficit with calories and watching carbs in the evening - I lost 5 lbs in approximately 3 weeks, Monday will be 4th shot.
As time passes and it is approved for prescription / we will have a leaflet to read of all side effects reported in by the group that is on the peptide. I should do a search for double blind placebo studies and read what the testing phases have reported.
Hope all is well. Typing with a cell, as I am travelling, apologies for any misspelling's or anomalies.
I used Reta at 1 mg, did go to 2 mg but found it made me nauseous so I settled on 1 mg for a few months. I paid for an ultrasound of my liver before starting, as people have read before I had a virus (mono) attack my liver and damage the organ. It caused mild fatty liver which turned into mild/medium fatty liver. I was having an ultrasound each year to ensure it was not progressing. I did get it to stop progressing with diet/supplements, but I want to heal it completely.
Reta and GLP-1 agonists will be used off label for fatty liver. Even people who did not lose weight in trials, in some studies, and were overweight/fat - still lost liver fat.
Anyway, I can't tell you how many months but I am guessing 4 or 5 and I finally had my Gov't paid ultrasound done and received the results. The radiologist compares the ultrasounds. I drop off my paid ultrasounds at the local hospital so they can use it for comparing. I also had a CBC/liver/kidney/lipid, etc. blood panel completed. Blood work was great. My ultrasound came back as the best ever, but still some fat in my liver. It was graded as 'less than mild and no need for medical intervention'.
Until recent the only treatment for NAFLD was diet changes/lose weight. I don't smoke, do rec drugs, and only drink a few times a year at functions and in moderation.
I know I lost a lot of BF and assume some was visceral fat, as your pants/belt doesn't lie lol. I had to punch two more holes in my belt and I lost approximately 10 lbs - 15 lbs.
Even though I lost weight, multiple people at the gym asked me what I was doing for my bulk. It was an optical illusion - I lost weight and did get more vascular/more lines but lost weight. More of a V look and muscles looked larger.
This was an experiment done under the safest protocols I could manage myself. Blood work, weekly urinalysis dips, BP daily, and keeping a journal how I felt / also progress in the gym. Starting weight, weight each week. I wanted to know before I started how my liver looked compared to how it looked afterwards. I have to check my journal, but believe I started this in June and stopped 1 mg per week approximately 2 weeks ago.

Working out on a deficit is the safest/best way to lose fat, but I still wanted to test Reta would get rid of all the fat in my liver. There are millions walking around with NAFLD and will never know unless it progresses to cirrhosis, scarring, cancer. For anyone who takes harsh liver PED's, liver enzymes are a good benchmark, but recommend asking your doctor for an abdominal ultrasound or pay for one yourself.
I had normal liver enzymes when my NAFLD was worse. My GGT would be mildly high periodically, but that is a subjective liver test as it is the most sensitive and a few drinks/tylenol and your GGT will most likely be high.
Just an update on my 'experiment'.
 
At some point this year or last year, i dont remember exactly when. It was when nick walker was teamed up with chase irons' brand of peptides. Anyways, Nick walker said that reta was an absolute game changer.....and this year he is the new Mr. O. His bubble gut has settled down and he came in absolutly shredded. His win was 100% attributed to the addition of reta to his program.
Even with this, countless other confessions of pros, regular gym goers, cb members, actors etc i personally feel that if your are still able to achieve your goals without it then you dont need it. So for me, i dont need it. At east not yet.
There may be a time in the future that it might useful for me but taking into consideration the dose related side effects and already having intestinal issues, im not sure that its for me. Risk v reward and all.
 
I used Reta at 1 mg, did go to 2 mg but found it made me nauseous so I settled on 1 mg for a few months. I paid for an ultrasound of my liver before starting, as people have read before I had a virus (mono) attack my liver and damage the organ. It caused mild fatty liver which turned into mild/medium fatty liver. I was having an ultrasound each year to ensure it was not progressing. I did get it to stop progressing with diet/supplements, but I want to heal it completely.
Reta and GLP-1 agonists will be used off label for fatty liver. Even people who did not lose weight in trials, in some studies, and were overweight/fat - still lost liver fat.
Anyway, I can't tell you how many months but I am guessing 4 or 5 and I finally had my Gov't paid ultrasound done and received the results. The radiologist compares the ultrasounds. I drop off my paid ultrasounds at the local hospital so they can use it for comparing. I also had a CBC/liver/kidney/lipid, etc. blood panel completed. Blood work was great. My ultrasound came back as the best ever, but still some fat in my liver. It was graded as 'less than mild and no need for medical intervention'.
Until recent the only treatment for NAFLD was diet changes/lose weight. I don't smoke, do rec drugs, and only drink a few times a year at functions and in moderation.
I know I lost a lot of BF and assume some was visceral fat, as your pants/belt doesn't lie lol. I had to punch two more holes in my belt and I lost approximately 10 lbs - 15 lbs.
Even though I lost weight, multiple people at the gym asked me what I was doing for my bulk. It was an optical illusion - I lost weight and did get more vascular/more lines but lost weight. More of a V look and muscles looked larger.
This was an experiment done under the safest protocols I could manage myself. Blood work, weekly urinalysis dips, BP daily, and keeping a journal how I felt / also progress in the gym. Starting weight, weight each week. I wanted to know before I started how my liver looked compared to how it looked afterwards. I have to check my journal, but believe I started this in June and stopped 1 mg per week approximately 2 weeks ago.

Working out on a deficit is the safest/best way to lose fat, but I still wanted to test Reta would get rid of all the fat in my liver. There are millions walking around with NAFLD and will never know unless it progresses to cirrhosis, scarring, cancer. For anyone who takes harsh liver PED's, liver enzymes are a good benchmark, but recommend asking your doctor for an abdominal ultrasound or pay for one yourself.
I had normal liver enzymes when my NAFLD was worse. My GGT would be mildly high periodically, but that is a subjective liver test as it is the most sensitive and a few drinks/tylenol and your GGT will most likely be high.
Just an update on my 'experiment'.
Yes, tylonal, for me it was a few days of tylonal 1's (my lower back was hurting pretty bad) prior to bloodwork that threw my enzyms high. Then i had ultrasound and liver fat test done. I do have some liver hemangiomas, i asume from my years of alcohal and rec abuse and possibly my use of anadrol/winstrol etc, but my liver fat was so little that the lady doing this test told me during the test "im not supposed to say results, but in your case, theres basically no fat in the liver at all, so you dont need to stress about results, your completely fine for this test" the signal returned so fast.
I used some tudca and milk thistle for a few months before the next bloodwork and my liver enzymes were excellent again.
Tylonal especially with opiates is very liver taxing.
Advil is apparentely harsh on the kidneys.
So use them really only when needed.
 
Yes, tylonal, for me it was a few days of tylonal 1's (my lower back was hurting pretty bad) prior to bloodwork that threw my enzyms high. Then i had ultrasound and liver fat test done. I do have some liver hemangiomas, i asume from my years of alcohal and rec abuse and possibly my use of anadrol/winstrol etc, but my liver fat was so little that the lady doing this test told me during the test "im not supposed to say results, but in your case, theres basically no fat in the liver at all, so you dont need to stress about results, your completely fine for this test" the signal returned so fast.
I used some tudca and milk thistle for a few months before the next bloodwork and my liver enzymes were excellent again.
Tylonal especially with opiates is very liver taxing.
Advil is apparentely harsh on the kidneys.
So use them really only when needed.
All NSAIDS are hard on the kidneys, stomach and intestines. Doctors used to hand out NSAID's - prescription strength for chronic pain like candy (Naproxen, IBUprofen when it was new(advil), high dose aspirin). Now doctors will recommend IBUprofen most often in fairly high dosages for short durations but no longer keep people on NSAIDS for decades like they used to. A relative had surgery on his spine, bad arthritis in his knee and had physio and a strong NSAID prescribed for 20 years. After 20 years, he had blood in his stool, stomach pain, and they scoped - he had an intestinal hole and ulcers.
Most 'newer' doctors admit to using Advil (IBUprofen) for bad pain in high dosages but not long term. When I was dealing with chronic pain, my doctor said there are many NSAIDS that would help, but in a few years your will be back with really annoyed kidneys or ulcers.
All medications must be metabolized and removed. Some are easier on the kidneys/liver than others. In the mixtures you refer to - such as percocet, or T3 - acetaminophen with codeine, whoever told you it was the narcotic that was stressing the liver was wrong. If you have pre-existing liver damage, the dosage has to be reduced but most narcotics are not hard on the liver. They are very addictive and I would have to be in pretty bad condition to consider taking any.
Not disagreeing with you as they do have to be removed by the liver in most instances with some kidney involvement, but it is most definitely the acetaminophen that is the liver toxic culprit.
If you have medical literature that indicates the opiate significantly makes the medication for pain worse, please post it as I would like to read it. People with serious pain issues and liver issues are usually prescribed medications like oxycontin vs. percocet because the latter has tylenol in it. Respect your comments @DeeKnows - I think you know I am not argumentative and the first to admit I learn from listening to others. This one I am pretty confident in, but I have been wrong many many times.
Acetaminophen is the leading cause of acute liver failure.
I am glad to hear your Hepatic steatosis is extremely mild. I suspect if everyone had an ultrasound, a lot of eyes would be open to the fact the liver will function efficiently until about 75% or more is damaged and at that point, it is a steep hill to climb. Hard to fathom, but the liver is resiliant but like all organs can only take so much before it says piss off.
 
@Goldenrod
It appears you are correct.
When my results came in i did a quick search. I just remember it saying that it was bad and my hunch about taking them prior to bloodwork was correct. I thought the opiates made it worse. I really didnt check if its worse with codiene.
I was always told that taking any opiate drugs would cause organ injury, so usually i stayed away from them unless in bad pain.

I shoudlve checked first before adding in especially with opiates without the facts.

Thanks for rectifying it for all of us.
I know it comes from a good place with you, no worries about that at all. And i actually really appreciate it. Better education is always appreciated on my end.
 
Yes, tylonal, for me it was a few days of tylonal 1's (my lower back was hurting pretty bad) prior to bloodwork that threw my enzyms high. Then i had ultrasound and liver fat test done. I do have some liver hemangiomas, i asume from my years of alcohal and rec abuse and possibly my use of anadrol/winstrol etc, but my liver fat was so little that the lady doing this test told me during the test "im not supposed to say results, but in your case, theres basically no fat in the liver at all, so you dont need to stress about results, your completely fine for this test" the signal returned so fast.
I used some tudca and milk thistle for a few months before the next bloodwork and my liver enzymes were excellent again.
Tylonal especially with opiates is very liver taxing.
Advil is apparentely harsh on the kidneys.
So use them really only when needed.
Cold water extract the codeine (and the caffine dissolves with the codeine) out of the t1's next time

Its really easy, crush the pills in a warm cup of water and stir well for a few minutes to dissolve, then place the cup in the fridge.

Once it has cooled to fridge temperature drink the clear portion, avoiding the white powder in the bottom (that is the Tylenol that separated)
 
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