Reta seems to impact people differently. If you suffer from anxiety but have it under control, per the comments above - it appears to exacerbate the issue.
That is a guess as it is still under controlled studies and has some negative health side effects, but from a fat burning peptide it is impressive.
If you have any pre-existing mental diseases (no different than diabetes and people should be proud to admit these diseases with a stigma, are an issue.) I would start out at .25 mg and titrate up every 2 weeks by .25 of a mg.
I can still eat, but when I increase it by .25 mg a week I notice it is hard to get my portions/meals down which I do so by eating more often in smaller amounts. I am only on a mild deficit with calories and watching carbs in the evening - I lost 5 lbs in approximately 3 weeks, Monday will be 4th shot.
As time passes and it is approved for prescription / we will have a leaflet to read of all side effects reported in by the group that is on the peptide. I should do a search for double blind placebo studies and read what the testing phases have reported.
Hope all is well. Typing with a cell, as I am travelling, apologies for any misspelling's or anomalies.
I used Reta at 1 mg, did go to 2 mg but found it made me nauseous so I settled on 1 mg for a few months. I paid for an ultrasound of my liver before starting, as people have read before I had a virus (mono) attack my liver and damage the organ. It caused mild fatty liver which turned into mild/medium fatty liver. I was having an ultrasound each year to ensure it was not progressing. I did get it to stop progressing with diet/supplements, but I want to heal it completely.
Reta and GLP-1 agonists will be used off label for fatty liver. Even people who did not lose weight in trials, in some studies, and were overweight/fat - still lost liver fat.
Anyway, I can't tell you how many months but I am guessing 4 or 5 and I finally had my Gov't paid ultrasound done and received the results. The radiologist compares the ultrasounds. I drop off my paid ultrasounds at the local hospital so they can use it for comparing. I also had a CBC/liver/kidney/lipid, etc. blood panel completed. Blood work was great. My ultrasound came back as the best ever, but still some fat in my liver. It was graded as 'less than mild and no need for medical intervention'.
Until recent the only treatment for NAFLD was diet changes/lose weight. I don't smoke, do rec drugs, and only drink a few times a year at functions and in moderation.
I know I lost a lot of BF and assume some was visceral fat, as your pants/belt doesn't lie lol. I had to punch two more holes in my belt and I lost approximately 10 lbs - 15 lbs.
Even though I lost weight, multiple people at the gym asked me what I was doing for my bulk. It was an optical illusion - I lost weight and did get more vascular/more lines but lost weight. More of a V look and muscles looked larger.
This was an experiment done under the safest protocols I could manage myself. Blood work, weekly urinalysis dips, BP daily, and keeping a journal how I felt / also progress in the gym. Starting weight, weight each week. I wanted to know before I started how my liver looked compared to how it looked afterwards. I have to check my journal, but believe I started this in June and stopped 1 mg per week approximately 2 weeks ago.
Working out on a deficit is the safest/best way to lose fat, but I still wanted to test Reta would get rid of all the fat in my liver. There are millions walking around with NAFLD and will never know unless it progresses to cirrhosis, scarring, cancer. For anyone who takes harsh liver PED's, liver enzymes are a good benchmark, but recommend asking your doctor for an abdominal ultrasound or pay for one yourself.
I had normal liver enzymes when my NAFLD was worse. My GGT would be mildly high periodically, but that is a subjective liver test as it is the most sensitive and a few drinks/tylenol and your GGT will most likely be high.
Just an update on my 'experiment'.