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We all know one item on its own may have benefits, we can mix a couple things together to enhance the effects, like adding grapefruit juice to some oral medications and oral gear. We know one chemical on its own may be rather inert, like baking soda. Now adding something can cause an extreme and potentially violent, or extreme reaction, like adding in an acid to BS.
Simple analogy but you get what i mean.
Ibuprofen is a dangerous drug on its own and not respected enough IMHO, ginko biloba which some of us use mixe with Ibuprofen can cause issues, many supplements mixed together cause issues.
Lord knows i have been lightheaded, low on sugar, fely nausea many a taime as i was experimenting with different combos.
See article above, crazy stuff. Be careful!!