Colon cancer: Could aspirin help slow disease progression?
A study found that aspirin can activate protective genes to inhibit and slow the progression of colon cancer.
www.medicalnewstoday.com
Interesting, I remember reading that Dr. David Sinclair, professor/scientist at Harvard university researching lifespan/anti-aging techniques also takes aspirin because of the research done on it and it's ability to prevent cancer as wellColon cancer: Could aspirin help slow disease progression?
A study found that aspirin can activate protective genes to inhibit and slow the progression of colon cancer.www.medicalnewstoday.com
One who made a billion selling a lab that was abandoned... now uses botox but not eager to remove his man boobs...Interesting, I remember reading that Dr. David Sinclair, professor/scientist at Harvard university researching lifespan/anti-aging techniques also takes aspirin because of the research done on it and it's ability to prevent cancer as well
i may consider taking some daily low dose
It's more the brain hemorages I'd be worried aboutAspirin and cancer treatment: systematic reviews and meta-analyses of evidence: for and against ,
British Journal of Cancer, November 2023
A comprehensive review on aspirin risks/benefits.
TLDR
Bleeding risks are overstated,
Aspirin use highly correlates with prevention of many types of cancer and metastases.
This bleeding risk was also discussed in the review. Hypertension being a coincident contributor to risk.It's more the brain hemorages I'd be worried about
Intracranial Hemorrhage With Low-Dose Aspirin in People Without Symptomatic Cardiovascular Disease
This systematic review and meta-analysis assesses the risk of intracranial hemorrhage associated with low-dose aspirin among individuals without symptomatic cardiovascular disease.jamanetwork.com
That's good, the study I posted was in patients without symptomatic cvd. I wonder if hypertension would be included or not. I didn't actually read it entirely some of the raw data is hard to understandThis bleeding risk was also discussed in the review. Hypertension being a coincident contributor to risk.
Unlike a gastrointestinal bleed, the consequences of a cerebral bleed, whether or not fatal, can be of a severity comparable to a cancer or a myocardial infarct in a risk/benefit evaluation. Estimates of additional risk in patients on aspirin are around one or two events per ten thousand (10,000) subject-years. The major factor in cerebral bleeding however is hypertension, and in an RCT of aspirin based on more than 18,000 hypertensive patients—all of whom were receiving ‘optimal’ antihypertensive treatment—there were no additional cerebral bleeds in patients randomised to aspirin.
Tell us more about David Sinclair selling an abandoned lab, I couldn't find anything by googling that, also I googled his net worth, and it just came up as 25 million.One who made a billion selling a lab that was abandoned... now uses botox but not eager to remove his man boobs...
All the major outlets, Reuters, Forbes, etc. https://duckduckgo.com/?q=GlaxoSmithKline+bought+sirtis+in+2008+for+$720+million&ia=webTell us more about David Sinclair selling an abandoned lab, I couldn't find anything by googling that, also I googled his net worth, and it just came up as 25 million.
I know he's unpopular for trying to patent NMN and stuff, and he's quite the self promoter but I haven't heard anything about fraud.
I will admit I have 30 min to go through a slew of threads and didn't read this article yet. Is it stating aspirin increases hypertension? I am asking because multiple studies show low dose aspirin taken at night (not during the AM) has the opposite effect. I have read enough, weighing good vs. bad to take low dose aspirin at least 4-5 days a week. From my reading no drug is perfect or I haven't found one as some people's physiology will put them at risk for issues, but this is as close to a wonder drug as any I have read about for knocking down %'s of different causes of morbidity or serious issues. Just my opinion. One of my relative had to stop a stronger NSAID due to intestinal bleeding but due to clotting issues still is prescribed a low dose aspirin daily and he has no bleeding issues. It was prescribed by his GP and surgeon who removed did two of the surgeries to prevent the need for further.This bleeding risk was also discussed in the review. Hypertension being a coincident contributor to risk.
Unlike a gastrointestinal bleed, the consequences of a cerebral bleed, whether or not fatal, can be of a severity comparable to a cancer or a myocardial infarct in a risk/benefit evaluation. Estimates of additional risk in patients on aspirin are around one or two events per ten thousand (10,000) subject-years. The major factor in cerebral bleeding however is hypertension, and in an RCT of aspirin based on more than 18,000 hypertensive patients—all of whom were receiving ‘optimal’ antihypertensive treatment—there were no additional cerebral bleeds in patients randomised to aspirin.
No, they just stated that hypertension is the major risk factor in cerebral bleeding.I will admit I have 30 min to go through a slew of threads and didn't read this article yet. Is it stating aspirin increases hypertension? I am asking because multiple studies show low dose aspirin taken at night (not during the AM) has the opposite effect. I have read enough, weighing good vs. bad to take low dose aspirin at least 4-5 days a week. From my reading no drug is perfect or I haven't found one as some people's physiology will put them at risk for issues, but this is as close to a wonder drug as any I have read about for knocking down %'s of different causes of morbidity or serious issues. Just my opinion. One of my relative had to stop a stronger NSAID due to intestinal bleeding but due to clotting issues still is prescribed a low dose aspirin daily and he has no bleeding issues. It was prescribed by his GP and surgeon who removed did two of the surgeries to prevent the need for further.
All the major outlets, Reuters, Forbes, etc. https://duckduckgo.com/?q=GlaxoSmithKline+bought+sirtis+in+2008+for+$720+million&ia=web
Then he responded to question on twitter with "" and blocked
I should have worded it different.GlaxoSmithKline wouldn't buy an abandoned lab for $720M, biotech is very rewarding if you are able to find something revolutionary, which is what he must have done to obtain a $720M cheque