All i can say is that from the test i have done with my TRT Dr and with LGC, the results have been very similar. Hormone testing does not require very much Blood. The finger prick at the Blood Services is enough to tell you your Hemoglobin and iron level. With LGC my test levels have tested to be within the range i anticipated they would be. For E2, its as good as any non sensative E2 test...its really meant as a guide anyways as E2 bounces around depending on how often you pin, diet, stress, body fat levels etc. I have done two tests in two weeks and gotten two different results. As my TRT Dr explained if you get tested regularly you get to establish a pattern, and the "standard" E2 test will be within a certain standard deviation (which will be different for everyone). If one out of 7 or 8 tests fall outside your normal parameters and you have no other symptoms of Low or high E2, ignore that single outcome....but I digress. Overall, i am confident in LGC results.