We need a gear porn thread

Few discontinued items that most likely won’t be able to ever get I have no idea when and if I’ll use but I’ll hold on to them like gold hahaha

Prosum : mast prop and tren ace
Pareto : ment , halotestin , anadrol tren e , tren ace
Citadel : tren e and tren ace
Syngen : mast e and TMT XR
 

Attachments

  • IMG_9954.jpeg
    IMG_9954.jpeg
    1.6 MB · Views: 64
Just seen the pics from this loser. Imagine being such a scum bag that you can afford to spend thousands on pharmacy HGH but then scam members on here for a couple hundred $.
That makes me sick to my stomach. Taking someone’s hard earned money and fucking off with it.
 
I don't know if this is what you're looking for, but here's a selection of funky and odd Innovagen products and my matching guitar and "gearbox". :cool:

Most of the rest of the stuff is just packed in boxes. I should make bigger, fancier boxes I suppose.

View attachment 100398View attachment 100399View attachment 100400
Man what are those terpene things? I’ve never heard or seen of that before. Heard of injectable CBD from enhanced 2 but not this. Do you need to smoke first for it to work or what? I hate pinning gear, let alone injecting random stuff like that lol. Unless it’s subQ
 
Man what are those terpene things? I’ve never heard or seen of that before. Heard of injectable CBD from enhanced 2 but not this. Do you need to smoke first for it to work or what? I hate pinning gear, let alone injecting random stuff like that lol. Unless it’s subQ
Terpenes are complex and very interesting in their activities in many ways. I was playing with a number of the Innovagen terpene preparations, particularly Alpha Ionone and Alpha Cedrene. That may be what you are looking at here. There are also some Cannabis potentiators in there that are just for fun, but the recovery and hypertrophy angles are mostly investigated for introducing some non-steroidal influence on hypertrophy through a different pathway(s).

I was doing a lot of back and forth with Inno in those days on these things and experimenting with them. I've found an email on the subject which I'll reproduce here, mostly regarding the cAMP system and terpenes:

Here's some stuff for you:

A muscle cell's activity can be influenced in two broadly distinct manners, intra-cellular nuclear receptors:
https://en.wikipedia.org/wiki/Steroid_hormone_receptor

and extracellular membrane receptors:

https://en.wikipedia.org/wiki/Membrane_steroid_receptor

https://en.wikipedia.org/wiki/Membrane_androgen_receptor



G-Protein Coupled Receptors (GPCRs). GPCRs are trans-membrane receptors that lead to signalling cascades, ultimately affecting the types of genes that are expressed in the cell. Once a ligand (a compound that has affinity for a receptor) binds to the receptor it can produce one of three responses. It can raise a receptor response above basal activity (agonist), cause a lack of response (antagonist), or cause activity to dip below basal levels (inverse agonist).
The binding of the ligand to the receptor leads to a signaling cascade that either decreases or increases the activity of a particular enzyme. These enzymes typically are responsible for the production of molecules known as secondary messengers like cAMP (cyclic adenosine monophosphate). The amount of secondary messengers present in a cell dictates the activity of other enzymes called kinases and phosphatases. The role of kinases is to phosphorylate (add a chemical phosphate group) and the role of phosphatases is to dephosphorylate (remove a chemical phosphate group) onto downstream target proteins. These target proteins are usually transcription factors, proteins that bind DNA and promote the expression of certain genes within the cell. We can think of the chemical phosphate group added to these transcription factors as on and off switches for the expression of certain genes.
Ligand → Receptor → Ligand-Receptor Complex → Enzyme → Secondary Messenger Production → Kinase and Phosphatase Activity → Phosphorylation or Dephosphorylation of target proteins → Gene expression


The membrane androgen receptor is just one example of a G-Protein Coupled Receptor and it’s endogenous ligand is testosterone.
The surface of the muscle cell expresses many different types of G-Protein Coupled Receptors that respond to a variety of ligands.

Brief 4 minute overview of GPCR activated cAMP





A deeper dive into cAMP and muscle cells (only if you like this kind of stuff….)

cAMP signaling in skeletal muscle adaptation: hypertrophy, metabolism, and regeneration
https://journals.physiology.org/doi/full/10.1152/ajpendo.00555.2011





Finally the point of all this was to introduce a-Ionone, a terpene found in violets, and other plants.
https://sci-hub.se/10.1039/c8fo01992d

To understand this paper:

"Recently, we undertook a phenotype-based approach to screening of compounds in C2C12 cells to look for small-molecule stimulators of myogenesis. Using this process, we found that α-ionone (C13H20O), an aroma compound found in a variety of plants including violets, blackberries, and plums, is a good candidate myogenic molecule that warrants further investigation (an unpublished finding). It has a sweet odor like violets and a woody, berry, and floral taste and is used as a food flavoring in beverages, ice cream, baked goods, and candy.
Its use worldwide is in the region of 100–1000 metric tons per annum. In this study, we investigated the potential of α-ionone in regulation of high-fat diet (HFD)-induced muscle wasting
and delineated the mechanisms involved."
The authors have to induce a condition to see if it can be corrected.

2 Important discoveries:
"α-Ionone promotes myogenesis via cAMP"

"Moreover, α-ionone significantly increased the mRNA expression of PGC-1α4 (a truncated form of PGC-1α1) and positively modulated the expression of PGC-1α4 targets genes, such as myostatin and IGF-1, in the skeletal muscle of HFD-fed mice. The amount of p-SMAD2/3 (a downstream molecule of myostatin signaling) significantly diminished, whereas the amounts of IGF-1 signaling molecules including p-AKT, p-mTORC, p-S6K1, and p-4E-BP1 significantly increased in the skeletal muscle of α-ionone-treated mice relative to untreated mice"

And here is a brief intro to understanding the thinking behind the use of Alpha Cedrene (another terpene) : https://www.ergo-log.com/alpha-cedrene.html
 
Last edited:
Few discontinued items that most likely won’t be able to ever get I have no idea when and if I’ll use but I’ll hold on to them like gold hahaha

Prosum : mast prop and tren ace
Pareto : ment , halotestin , anadrol tren e , tren ace
Citadel : tren e and tren ace
Syngen : mast e and TMT XR
Those sachets look like syn
 
There are some similarities I noticed also

Pareto near the end thieir sachets were similar to old syn
With the molecule and top peel off

They were once both at the top of the game for a long time
Huh, well how about that. Got to see if I got any older stuff from them to post, but after looking at the pic, it definitely looks very similar
 
Top