Mesalamine and Colitis

FitTrader

FitTrader

Well-known member
Trusted Member
What’s up guys ,

So my girlfriend has been diagnosed with UC
She’s had it for a few years.
Recently she did bloood work and the levels were 10x out of range so she had to do a colonoscopy. The doctor prescribed her mezavant. After a few days she felt her symptoms get worse , bathroom 20x a day and pain and the Dr told her to stop it.

Yesterday she saw doctor and they said ok try Pestana ( mesalamine) 4g a day (4x 1g pills)

we woke up , had our breakfast , she took half the dose just in case and Dr said maybe to start slow since the last one had severe sides.

Around 12 she tells me she doesn’t feel good and is coming back home
That she feels sick and stomach hurts
Any other day I’d be like oh boy but I knew she took the new medicine

She looked like a zombie could tell she really didn’t feel good.. few hours of resting go by
She tells me she wants to shower and to come help her

She starts to shower and then closes the water and says I really don’t feel good started getting wobbly… she gets out sits down at toilet and convulsively vomits 2 huge times….

And then she falls over… fully stiff convulsing
.. I go babe babe.. and she’s not responsive.. she’s shaking and her pupils are dilated and her lips are white as a ghost

So now I am like
Oh fuck This is bad call 911 and they are absolutely useless
After about 60-80 seconds she regains consciousness

Paramedics come and check her vitals
She’s doing better

I am not well versed in autoimmune diseases and all but these 2 drugs are extremely potent

She must have some allergic reaction to them and personally I think this is not the proper route to take to deal with UC

Anyone have any experience ?
 
Side note
I didn’t know that some type of fainting is similar to a seizure

Learned that today hands on

Paramdic explained it’s the body dropping blood pressure… it’s not a seizure.. similar to when people tense up and shake when they fall from getting punched

I’m happy it wasn’t a seizure
 
Well I found out, I had ulcerative colitis back in 1997 or showed the first symptoms went I did the Mr Kingston show...level 2.

I took Asacol...mesalazine since 2001. 2.4 grams a day and went as high as 8 grams per day.

I had upset stomach, burped up acid...need a script for a antacids refulx meds.
I been off the tabs, since 2001. My doctor told me to take vitamin D, no more colitis unless I go under 3000iu per day.
Sorry to hear, how your girlfriend feels on these drugs. Plus the side effects with these drug, and I know off almost everyone that can't take them anymore way too many issues.
 
Hey @FitTrader - scary shit pardon the pun. Seriously though, sorry for you and the girlfriend. I have two family members and they are both treated differently and not in the same manner as your girlfriend.
One person takes high dose enteric coated aspirin - I forget the name of it but will ask her and she takes it after meals and is 100% fine and has been. She had one hick up when her white cells were super low and they think it had to do with the aspirin (or the derivative of aspirin - I have to read up on the drug. It is very high dose but has a coating so it gets absorbed in the lower intestine I believe. Something tells me it is called Salofalk which I believe may be the same medication. She has to frig with the dosage based on how bad she is. I was under the impression from listening to her and reading the label, it was essentially like a high dose strong medication / similar drug as aspirin.

Another one of my family is an idiot and eats shit food and triggers that cause it to flare and does nothing to try to control it. He has to go to the hospital once a month or once every few months for an IV of a drug that controls his immune system like Remicaid. It controls your immune system but also makes you susceptible to other issues as it is knocking down your immune system. Costs a fortune for one treatment.
We can talk about it now as it is legal but at first he was able to control it with CBD oil and eventually he moved to a mix of CBD and THC oil - I didn't read up on it but he indicated the doctor approved the treatment and there is some science / studies showing it can help.

my experiences were all other people I watched who were good and it was under control or were having flare ups and literally had no control and would go to the bathroom in their pants if they couldn't get to a toilet immediately.

I don't know enough about this disease or how it may be treated naturopathically but I know it is your immune system attacking itself which causes inflammation, and with the people I know terrible diarrhea. I recall being told certain foods and stress are triggers. @Funnyman - would know much better than I do. I will read my Naturopathic books if they contain sections on this if you want me to. Keep in mind I am no doc and it would simply be regurgitating info I read. May or may not help. Hopefully, they can find something fast - that works and doesn't have bad side effects.
Regardless - sorry and that would be extremely scary. Best of luck - she is lucky to have you to support her.
 
Originally, BPC 157 appears as a cytoprotective antiulcer peptide, stable in human gastric juice, previously employed in ulcerative colitis clinical trials and now in those concerning multiple sclerosis.

It's too bad this wasn't regulated for human use. I hope you figure everything out brother.
 
She will be precribed meds up the chain of severity and response until she gets better. Problem is sometimes u get too sick too fast and by the time u get the right meds it may be surgury time.
Not being a dick, this is the reality of UC and crohns ibd illnesses. Search up crohns and colitis foundation canada and you can see the meds and how they increase up the ladder. Biologics are top tier, expensive and can cause lymphoma. Im blunt with it cuz thats the reality. Sorry. Some of the meds cause severe side effects that may not be tolerable, she should tell doc asap to switch to another.
 
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